tina huang data scientist

PubMedGoogle Scholar. For ds_halfUDG libraries, we masked 2bp from both ends of the reads with trimBam in bamUtil 1.0.13 (https://github.com/statgen/bamUtil) to remove the damaged sites. We generated genome-wide sequencing data for 102 newly reported hunter-gatherers, and increased coverage for 14 previously published individuals4. 5 Cliches About computer science flow chart You Should Avoid, What Freud Can Teach Us About brief candle in the dark my life in science. Wyprodukowany w konwencji anime serial stanowi spin-off produkcji "Midzy nami, Misiami", ktrej reyserem wykonawczym . & Hlie, J. F. Temperature and precipitation regime in LGM human refugia of southwestern Europe inferred from 13C and 18O of large mammal remains. 9; the entire IT and laboratory teams at the Department of Archaeogenetics of MPI-SHH for technical assistance; M. Meyer and S. Nagel for support with single-stranded library preparation; K. Post, P. van Es, J. Glimmerveen, M. Medendorp, M. Sier, S. Dikstra, M. Dikstra, R. van Eerden, D. Duineveld and A. Hoekman for providing access to human specimens from the North Sea (The Netherlands); M. D. Garralda and A. Estalrrich for providing access to human specimens from La Riera (Spain); J. Grski andM. Zajcfor providingaccess tohuman specimensfromMaszycka cave;C. Di Patti for providing access to human specimens from San Teodoro 2 (Italy); P. Blaeviius for providing access to the Donkalnis human remains and the new radiocarbon dates; the Italian Ministry of Culture and Soprintendenza Archeologia Belle Arti e Paesaggio for the Provinces of Verona, Rovigo, and Vicenza for granting access to the human remains of Tagliente 2; F. Fontana, who carries out investigations of the Riparo Tagliente site (Italy); the Friuli Venezia Giulia Superintendency for providing access to the human tooth Pradis 1; and the Soprintendenza Archeologia Belle Arti e Paesaggio for the Provinces of Barletta-Andria-Trani and Foggia for providing access to the Paglicci human remains. PubMed The Gravettian from a palaeodemographic point of view. Mateja Hajdinjak, Fabrizio Mafessoni, Svante Pbo, D. M. Fernandes, D. Strapagiel, R. Pinhasi, Pavel Flegontov, N. Ezgi Altnk, Stephan Schiffels, Daniel M. Fernandes, Kendra A. Sirak, David Reich, Sandra Oliveira, Kathrin Ngele, Mark Stoneking, Eirini Skourtanioti, Harald Ringbauer, Philipp W. Stockhammer, Vanessa Villalba-Mouco, Marieke S. van de Loosdrecht, Wolfgang Haak, Joseph H. Marcus, Cosimo Posth, John Novembre, Natalija Kashuba, Emrah Krdk, Anders Gtherstrm, Nature 18 and Supplementary Data 2.O), suggests the Balkans as a source of the incoming Epigravettian-associated population. 116, 105100 (2020). Our knowledge of the genetic relatedness and structure of ancient hunter-gatherers is however limited, owing to the scarceness and poor molecular preservation of human remains from that period3. The youngest individual carrying large portions of hunter-gatherer ancestry in the analysed dataset is from Ostorf in northern Germany, dated to around 5.2ka (>90% Oberkassel clusterplus Sidelkino-clustercomponents)(Supplementary Data 3.F). Check it out! Check out Bootcamps Yes or nah? Quat. Contrary to the proposal in Fu et al.4 but in agreement with Petr et al.17, we do not observe a substantial decrease of Neanderthal ancestry in most European hunter-gatherers through time (Supplementary Information, section6 and Supplementary Figs. Mathieson, I. et al. Taipei, Taiwan . 2022 Fab Business Solutions - All Rights Reserved. This project has received funding by the European Research Council under the European Unions Horizon 2020 research and innovation programme under grant agreements no. Now we have the founder and CEO of YSYS, Deborah Okenla. 5, 820825 (2021). Interviewed Taiwanese designers and analyzed the interview data. 132, Tables 14 and references. Mathieson, I. et al. My name is Tina Huang and I'm a data scientist at a FAANG company. Martiniano, R., De Sanctis, B., Hallast, P. & Durbin, R. Placing ancient DNA sequences into reference phylogenies. Nat. Were dedicated to providing you the best ofNews, with a focus on dependability andBusiness. This finding, in conjunction with the genetic affinity of the Villabruna cluster to ancient and present-day Near Eastern ancestries4,15,16 (Supplementary Information, section8, Supplementary Fig. Reducing microbial and human contamination in DNA extractions from ancient bones and teeth. Maier, A. Evol. First, we show that individuals associated with the Gravettian culture across Europe were not a biologically homogeneous population. Natl Acad. Connect with them: Email: hellotinah@gmail.com. Biol. Her advice appears very solid, and she knows about the difficulties and barriers students are faced often when preparing for job interviews. . performed mortuary practices analyses. Think about some of your favorite apps today: Instagram, Uber, Facebook, and YouTube. The nucleolus is the largest substructure in the nucleus, where ribosome biogenesis occurs. Dismiss. Jodie Sweetin. The phylogenetic reconstruction of Epigravettian-associated genomes, with Pradis 1 diverging more deeply than all others, indicates that the turnover took place much earlier than 17kathe date of the more derived Tagliente 2 genome. Every Thursday, I share insights from books, learning & productivity tips, and a coding challenge. 5). Natural Language Processing (NLP) is another technique that has a well-deserved position in product development. We tested the affinity of Tutkaul 1 to worldwide ancient and modern populations relative to AG3. Shes the founder of Coding Black Females, a nonprofit with the aim to provide opportunities for Black female developers to develop themselves, meet familiar faces, network, receive support, and build relationships through having regular meetups., Check out the Coding Black Females website. Curr. Harris, K. & Nielsen, R. The genetic cost of Neanderthal introgression. When expanded it provides a list of search options that will switch the search inputs to match the current selection. Correspondence to 9). Edit your profile. Skoglund, P. et al. Nat. Bortolini, E. et al. All Rights Reserved. We applied ANGSD 0.93470 and hapCon71 for libraries from male individuals, and applied contamLD72 and a newly developed method that analyses contamination in ROH for female and male libraries (see Supplementary Information, section2 for a detailed description). We show that all analysed Epigravettian-associated individuals carry a homogeneous Villabruna ancestry, with the intra-group genetic structure mainly determined by their geographical, and not temporal, distribution. Both double-stranded and single-stranded libraries were further amplified with IS5/IS6 primers to reach a concentration of 200400ng/l as measured on a NanoDrop spectrophotometer (Thermo Fisher Scientific). 1c and Extended Data Fig. Paradis, E., Claude, J. The developed methyl gallate/cellulose acetate membrane exhibited PWF of 56.28 2.10 L m -2 h 1 and rejection rates of 99.14 0.03 % against oil emulsion. 5b and Supplementary Figs. Yu, H. et al. We looked at data on how many people had been dropped, the time when they were dropped, and the time they were found. Biol. Cassidy, L. M. et al. This is perfect for those of us who haven't a clue what to expect from data science - SQL portion - interviews. The three squares highlight Baltic HG groups associated with the Comb Ceramic Culture (CCC) that show a marked increase in Sidelkino-related ancestrycompared to olderBaltic HG groups. Internet Explorer). As of right now, it doesnt seem that MySQL is the right choice for storing data because the database is so large, it would be impossible to find and query the necessary information. a, Population structure among Epigravettian-associated populations revealed by a neighbour-joining tree based on pairwise f2 genetic distances. 7,794 Followers, 14 Following, 9 Posts - See Instagram photos and videos from Tina Huang (@hellotinah) hellotinah. It encourages me to go out and re-learn SQL and excites me for the mock interviews to come. The mtDNA contamination was estimated by Schmutzi (--notusepredC --uselength)69 for all the libraries. In other words, youll never have to worry about validity issues or having to re-take the course after a certain amount of time. The colours correspond to the grouping of tested populations, dots refer to the f4-values and the dark and light error bars to 1*SE and 3*SE estimated from 5 cM block jackknife, respectively. Instagram has an infinite scroll, and Uber has different options such as UberXL and Uber Pool. Ecol. Her YouTube channel is dedicated to data and computer science, including how to educate yourself in these topics. About the author: Tina Huang is a data scientist at one of the FAANG companies. Nat. EAGER: efficient ancient genome reconstruction. Freshwater radiocarbon reservoir effects at the burial ground of Minino, Northwest Russia. For the placement of individuals onto a Y-chromosomal phylogenetic tree (Extended Data Fig. Okenla is also part of Atomicos Angel Programme 2021, and is an advisory board member for both Coders of Colour and the No.10 Innovation Fellowship. The x-axes report the geographic regions as divided in Fig. Nature 615, 117126 (2023). PubMed However, the research team found no evidence for this, on the contrary: hunter-gatherer populations associated with the Gravettian culture and living in central and southern Europe are no longer genetically detectable after the LGM. "Unlike diving into the university life directly, the pathways program is a buffer that allows international students to be better prepared. For phylogenetic reconstruction (Extended Data Fig. To bind DNA, silica columns for high volumes (High Pure Viral Nucleic Acid Large Volume Kit (Roche)) were used. 537, 2432 (2020). Article Our capabilities include CNC machining, sheet metal The grouping of Epigravettian-associated populations is shown with the same colour in a. Evol. Hollywood Heights. Dev. Google Scholar. Madrid, Madrid, Spain. As inferred from the archaeological record35, the spread of the Magdalenian across Europe is linked to southwestern to northern and northeastern post-LGM population expansions and not to movements from southeastern refugia34. It involves lots of hypothesis testing and statistics which 365 Data Science also has a wonderful course on. Kristen Bell. Upper Palaeolithic genomes reveal deep roots of modern Eurasians. Currently use of the word 'vape' now means "to inhale and exhale the vapor produced by an . PubMed Some of those early groups from more than 40ka further admixed with Neanderthals, as shown by signals of recent introgression in individuals from Bacho Kiro in Bulgariaassociated with an Initial Upper Palaeolithic (IUP) archaeological cultureand from Petera cu Oase in Romania2,6. . This button displays the currently selected search type. & Steinrcken, M. Parental relatedness through time revealed by runs of homozygosity in ancient DNA. By submitting a comment you agree to abide by our Terms and Community Guidelines. Dismiss. Nat. The membrane was able to achieve FRR of 98.73 0.83 % after 4 cycles of filtration, indicating that anti-fouling properties have been enhanced. Commun. The f4-statistics were calculated by qpDstat 755 with parameter f4 mode: YES, with the Mbuti.DG population from Africa used as outgroup in all f-statistics analyses. Evol. Dotted lines delimit geographic regions described in the text. b, Population diversity shown by PMR between individuals in different groups. My name is Tina and I'm a data scientist and YouTuber. The number of individuals in each group is written to the right of each bar. The incoming Villabruna ancestry later became the most widespread hunter-gatherer ancestry across Europe. Required fields are marked *. On the basis of f4-statistics, we find that individuals assigned to the Oberkassel cluster are closer to the Arene Candide 16 genome than any other Epigravettian-associated group from Italy (Supplementary Data 2.F). The genomic history of the Iberian Peninsula over the past 8,000 years. Extensive farming in Estonia started through a sex-biased migration from the steppe. Instead, for the two SNPs associated with skin colour (SLC24A5 (rs1426654) and SLC45A2 (rs16891982)), Sidelkino clusterand Ukraine HG groups show a higher frequency (>90% for SLC24A5 and 2961% for SLC45A2) of the derived alleles related to light skin colour, compared with Oberkassel and Villabruna clusters, where those alleles are almost completely absent (<1%). L. Sineo, M.L. It was awesome seeing the thought process behind each of the questions - it helps students immensely! BMC Bioinformatics 15, 356 (2014). She majored in mathematics before switching to computer science. Lazaridis, I. et al. Charlene Hunter is a developer and an incredible advocate for increasing diversity in tech. Corporate Financial Managementspring term (BS 2508) Second year of undergraduate. We built 1 to 8 single- and double-stranded genetic libraries for each individual and enriched them for human DNA on 1.24million single nucleotide polymorphisms6 (SNPs), which were then sequenced and yielded 0.04- to 7.64-fold coverage on average over the targeted SNPs. Follow Author. Search 210,843,632 papers from all fields of science. Dismiss. I hold a Bachelor's degree at the University of Toronto where I studied pharmacology. These models are easy to implement as well as really helpful in deciding what to build and how much to invest in it. Its mainly used in industries such as finance, insurance, healthcare, and insurance-related apps such as credit card applications, vehicle purchasing, etc. I am Tina Huang, PhD, a data scientist, and the director of the Data Science Learning Center at the University of Arizona. Her YouTube channel advises data science jobs, self-study, boosting productivity, resume reviews, etc. Hi! These European regions, therefore, constitute climatic refugia where human populations survived during the LGM. Fu, Q. et al. Moreover, two of the oldest published groups from western Russia belonging to the Sidelkino clusterPeschanitsa (13ka)43 and the newly reported Minino individuals (11ka)showed extra affinity to the Oberkassel cluster, possibly owing to variability in this ancestry proportion during the initial formation phase of the Sidelkino-ancestry profile. The idea of data warehousing is to store large amounts of data in a way that makes it easier to extract and analyse. The hunter-gatherers were grouped based on their geographic origins and dates (Supplementary Information, section5). Write for us- Weird Science, Energy & Minerals Guest Post. Moreover, none of the Epigravettian-associated individuals have more affinity to southern European than to central-eastern European Gravettian-associated groups, as shown by f4(Mbuti, Epigravettian-associated individual/group; Vstonice, Paglicci 12) that is consistent with 0 (Supplementary Data 2.G). Brunel, S. et al. Sci. Yang, M. A. et al. Her YouTube channel is dedicated to data and computer science, including how to educate yourself in these topics. Google Scholar. Data Engineer Cover Letter Sample and Template. Further palaeogenomic studies on Upper Palaeolithic individuals from the Balkans will be essential for understanding whether southeastern Europe represents the source of the Villabruna ancestry and a climatic refugium for human populations during the LGM. Ancient genomes show social and reproductive behavior of early Upper Paleolithic foragers. The sample size of individualpairsincluded in each groupis reported in SupplementaryData 3.A. The Villabruna ancestry later appeared in central Europe and it is thought to have largely replaced groups related to the GoyetQ2ancestry4. Created by DataSciencePR. However, the genetic profile of contemporaneous Gravettian-associated individuals from western Europe remains unknown, as is their contribution to populations after the LGM. Initial Upper Palaeolithic humans in Europe had recent Neanderthal ancestry. Save my name, email, and website in this browser for the next time I comment. Taiwan Patent Application M401603, filed 11th April . Oxidation of methane into valuable chemicals, such as C 2+ molecules, has been long sought after but the dilemma between high yield and high selectivity of desired products remains. Rivollat, M. et al. Moreover, the almost complete genetic replacement of the Magdalenian-associated gene pool raises the hypothesis that parts of Europe were differentially populated during the abrupt climatic variation starting around 14.7ka with the BllingAllerd warming period, creating areas where southern European populations could expand. However, one of my favorites is using supervised learning techniques, such as random forest, SVM, and XGBoost, to discover which features contribute the most to the success of a product. Science 328, 710722 (2010). Check out Do Deepfakes Have Fingerprints? 8 Changes of Sidelkino and Oberkassel ancestry proportions in post-14 ka hunter-gatherers. Archaeological background, method descriptions and discussions additional to the main text, including sections 113, Figs. Look here to get updated on my recent favourite books, animes, filming equipment and more! Genome Res. Sci. This suggests that between the Early/Middle and Late Gravettian there was an east-to-west expansion of the Vstonice-associated ancestry that reached central-western Europe and created a longitudinal admixturecline between those two genetically distinct pre-LGM populations. 771234-PALEoRIDER (to W.H. She then served as a postdoctoral associate at the National Institute of Standards and Technology. Its no surprise that she was selected for the Code Cup, a yearly event where students from all over the world compete in coding challenges. Using DATES software, we estimated the admixture between Villabruna/Oberkassel and ANE ancestries in these old Sidelkino-cluster-related individuals to around 1513ka (Extended Data Fig. Each bar represents one individual with the ROH grouped in four length categories (grouped by colour). The IntCal20 Northern Hemisphere radiocarbon age calibration curve (055 cal kbp). The ancestry found in individuals associated with the preceding Aurignacian culture from central Europe (GoyetQ116-1ancestry) gave rise to Gravettian-associated individuals from western and southwestern Europe. A hands-on course covering SQL setup and fundamental components, combined with a guided walkthrough of 10 mock interviews with real-world SQL interview questions and expert tips on how to pass them successfully. E.A. Using Y-chromosome capture enrichment to resolve haplogroup H2 shows new evidence for a two-path Neolithic expansion to Western Europe. Int. The generation time is set to 29 years and the error bars show the SE of the admixture date estimated from jackknife resampling (n=22 autosomal chromosomes). Tina K. Sorensen. Nat. 1). Este botn muestra el tipo de bsqueda seleccionado. Villalba-Mouco, V. et al. She supports Propel on the business and marketing side. Do you agree to our cookie policy? Similarly, the SMS spam collection data achieves 99.20% for the validation and 99.10% for testing. Track your course progress, set daily goals, and make success a routine. My experience includes an internship at Goldman Sachs where I did some machine learning work before I took up my current data science job in tech. TV Actress. Xiamen Guansheng Precision Machinery Co Ltd is a company integrating R&D, production and sales. Financial support for ScienceDaily comes from advertisements and referral programs, where indicated. In addition, those groups also carry affinity to ANF suggesting more complex genetic processes behind their demographic history16. However, its formation, diffusion and interaction with contemporaneous hunter-gatherers from eastern Europe and their interplay with later expansions of Neolithic farmers from southeastern Europe are not well characterized. Revise SQL essentials, improve your communication style and tackle the most challenging follow-up questions with ease. Korneliussen, T. S., Albrechtsen, A. Article Saag, L. et al. Ontario Institute for Cancer Research Toronto, ON. First Name Tina #39. This might have been in part triggered by the concomitant expansion of Neolithic farmers across Europe and/or by environmental factors, such as the climatic event around 8.2ka, the largest abrupt cooling in the northern hemisphere during the Holocene epoch46,47. Wren, C. D. & Burke, A. Habitat suitability and the genetic structure of human populations during the Last Glacial Maximum (LGM) in Western Europe. 31, 29732983.e9 (2021). Double-stranded DNA libraries were built from 25l of DNA extract, without the presence of uracil DNA glycosylase (ds_nonUDG) or in the presence of uracil DNA glycosylase (ds_halfUDG), following a double-stranded UDG-half library preparation to reduce, but not eliminate, the amount of deamination-induced damage towards the ends of ancient DNA (aDNA) fragments58. Conversely,additional Oberkassel ancestry is identified in eastern Europe by at least 7.5ka in newly generated genomes from Minino I and Yazykovo from the upper Volga region, whereasa 1,000-years-older individual from Minino I did not have this genetic component. A series of f4-symmetry statistics confirm that all the Epigravettian-associated individuals are cladal, and do not share excess affinity with any local (Paglicci 12) or non-local preceding ancestries (Goyet Q116-1, Kostenki 14, Malta 1 or Vstonice) (Supplementary Data 2.F). A phylogeographic reconstruction of different lineages carrying this ancestry further suggests its entry point into northeastern Italy from the Balkans followed by a north-to-south expansion into the Italian peninsula alongside a population decline through sequential bottlenecks. What is Kagi Chart in Data Visualization? @hellotinah. 3.Tina Huang. 2. 2c). Tina is a computer science student at Stanford University. Nature 570, 182188 (2019). My name is Tina Huang and Im a data scientist at a FAANG company. Quat. A Free Service of Your Local Public Library and the Pennsylvania Public Libraries Film Center of the State Library of Pennsylvania Touchstone Pictures In celebration of our twentieth animated feature, we invite you to relive with us the story telling magic, the wit, the wisdom, the humor, the understanding of a very special person who gave the world a timeless and universal art form. An expert in the industry, and a tireless advocate for improving it, Areej AbuAli is an inspiring person for those in the SEO space. Nature 582, 384388 (2020). Genetics and material culture support repeated expansions into Paleolithic Eurasia from a population hub out of Africa. Gnther, T. et al. With the statistics f4(Mbuti, Fournol 85; Vstonice, test) and f4(Mbuti, Vstonice; Fournol 85, test), we show that all Vstonice-cluster individuals are significantly closer (|Z|>3) to the Vstonice group (n=5) and the Fournol-cluster individuals are closer to Fournol 85, whereas the geographically intermediate Gravettian-associated Goyet group shows extra affinity to both clusters (Fig. Tina Huang is one of the top three students to show up to compete. No, there are no prerequisites for enrolling. In the video above, she explains the two major components of big data: data warehousing and data science. As the coverage for most ancient samples was not sufficient for diploid genotype calling, we counted the reads covering selected phenotypic SNPs on reference or alternative alleles and computed the group-based allele frequencies following a maximum likelihood approach described in Mathieson et al.37. Notably, the Fournol ancestry provides a better proxy than Goyet Q116-1 for the genetic component found in the GoyetQ2 cluster and in El Mirn (Supplementary Data 2.H). Populations headed south? PubMed A genome sequence from a modern human skull over 45,000 years old from Zlat k in Czechia. Surprisingly, the research team found that populations from different regions associated with the Gravettian culture, which was widespread across the European continent between 32,000 and 24,000 years ago, were not closely related to each other.

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